Table 3.
Differential distribution of CCL5 -403/-28/In1.1 haplotypes in patients with severe EV71 disease and asymptomatic control subjects
Haplotype | -403 | -28 | In1.1 | Case (%) | Control (%) | OR (95% CI)* | P value* |
---|---|---|---|---|---|---|---|
h 1 | G | C | T | 113 (64.9) | 87 (76.3) | 1.000 (ref.) | – |
h 2 | A | C | C | 37 (21.3) | 18 (15.8) | 2.36 (1.08–5.13) | 0.032 |
h 3 | A | G | C | 21 (12.1) | 9 (7.9) | 2.31 (0.79–6.74) | 0.13 |
h 4 | A | C | T | 3 (1.7) | 0 | – | – |
CI = confidence interval; EV71 = Enterovirus 71; OR = odds ratio.
For results shown in bold, P < 0.05. Global haplotype association P value: 0.052.
Age-adjusted logistic regression models using the SNPstats software.