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. 2015 Oct 7;10(10):e0138592. doi: 10.1371/journal.pone.0138592

Fig 3. The 4 extract types of HBPDS have a similar effect on neurological impairment in EAE mice.

Fig 3

(A-D) To investigate the most efficacious extract of HBPDS for treating neurological impairment in EAE mice, the 4 conditions selected according to Fig 2 were compared. Onset-treatment with DW- (20 mg/kg), 30% ethanol- (15 mg/kg), 70% ethanol (30 mg/kg), and 100% ethanol extracted (10 mg/kg) HBPDS had a similar effect on neurological impairment (A and B) in EAE mice; however, 30% and 100% ethanol-extracted HBPDS were slightly more effective. Sum of behavioral score (B) indicates the sum of score after onset-treatment with HBPDS. Data are expressed as mean scores ± SEM. (ANOVA test; ##p < 0.01 compared to normal control mice, **p < 0.01 versus EAE mice).