TABLE 1.
Baseline characteristics
|
Patients
|
||||
|---|---|---|---|---|
| All (n=90) | 2008–2009, seasonal influenza (n=25) | 2009–2010, influenza A(H1N1) pdm09 (n=65) | P | |
| Age, mean ± SD | 55±17.2 | 63±17.3 | 52±16.4 | 0.008 |
| Female sex | 42 (46.7) | 14 (56.0) | 28 (43.1) | 0.27 |
| History of outpatient corticosteroid use | 15 (16.7) | 3 (12.0) | 12 (18.5) | 0.54 |
| History of diabetes | 24 (26.7) | 6 (24.0) | 18 (27.7) | 0.72 |
| History of hypertension | 39 (43.3) | 14 (56.0) | 25 (38.5) | 0.13 |
| History of coronary artery disease | 16 (17.8) | 8 (32.0) | 8 (12.3) | 0.06 |
| History of renal failure | 5 (5.6) | 3 (12.0) | 2 (3.1) | 0.13 |
| History of cancer | 9 (10.0) | 2 (8.0) | 7 (10.8) | 1.00 |
| History of asthma or COPD | 43 (47.8) | 12 (48.0) | 31 (47.7) | 0.98 |
| APACHE II score, mean ± SD | 19.8±8.3 | 20.3±7.3 | 19.7±8.7 | 0.76 |
| LIS, mean ± SD | 2.0±1.1 | 1.5±1.0 | 2.3±1.1 | 0.005 |
| LIS >2.5 | 28 (31.1) | 4 (16.0) | 24 (36.9) | 0.055 |
| Total SOFA score, mean ± SD | 7.0±3.8 | 5.8±3.5 | 7.5±3.9 | 0.058 |
| Cardiovascular SOFA score, mean ± SD | 0.96±1.4 | 1.0±1.4 | 0.9±1.4 | 0.73 |
| Cardiovascular SOFA score >1 | 24 (26.7) | 7 (28.0) | 17 (26.2) | 0.86 |
Data presented as n (%) unless otherwise indicated. All scores are from intensive care unit admission. APACHE Acute Physiology and Chronic Health Evaluation; COPD Chronic obstructive pulmonary disease; LIS Lung injury score; SOFA Sequential Organ Failure Assessment