Table 1.
PD-ICA subcortical anatomical areas
| Brain area | Sub-areas | Z-score L/R | Peak coordinate L/R |
|---|---|---|---|
| Entorhinal cortex | – | na (2.94)/3.1 | −20, −7, −32/19, −4, −34 |
| Claustrum | – | na/4.3 | na/36, 0, −21 |
| Amygdala | Basolateral | 3.8/4.1 | −23, −5, −21/22, −4, −20 |
| Hippocampus | Dentate Gyrus | 4.7/4.2 | −34, −18, −14/34, −15, −17 |
| Substantia nigra | – | 5/4.9 | −8, −18, −15/7, −17, −15 |
| Periaqueductal gray | – | 5.6/5.4 | −3, −34, −12/3, −33, −12 |
| Pedunculopontine nucleus | – | 4.7/4.6 | −6, −30, −11/6, −29, −11 |
| Hypothalamus | – | 3.4/4.2 | −5, −3, −11/4, −3, −11 |
| Hippocampus | CA1, CA2, CA3 | 5.3/4.5 | −30, −27, −10/31, −27, −11 |
| Subthalamic nucleus | – | 5.2/5.2 | −8, −16, −10/9, −16, −10 |
| Nucleus accumbens | – | 5/4.9 | −9, 11, −9/8, 11, −8 |
| Basal forebrain | BNST | 3.3/3.6 | −6, 4, −8/9, 3, −10 |
| Basal forebrain | Extended amygdala | 6/5.8 | −16, −6, −8/10, −6, −8 |
| Basal forebrain | Substantia innominata | 3.6/5.1 | −8, 0, −8/8, 0, −8 |
| Putamen | Anterior putamen | 5.6/4.8 | −25, 11, −5/25, 11, −5 |
| Putamen | Posterior putamen | 6.1/4.8 | −30, −12, −6/31, −15, −2 |
| Globus pallidus | Internal + external | 5.7/4.7 | −20, 1, −1/21, −3, −3 |
| Caudate nucleus | Head | 8.2/6.2 | −10, 12, 4/10, 10, 2 |
| Pulvinar | Medial/Lateral | 5.3/4.5 | −19, −31, 5/11, −26, −4 |
| Thalamus | Ventrolateral/Ventroanterior | 5.3/3.6 | −17, −14, 11/14, −14, 12 |
| Caudate | Body | 4/4.8 | −15, 11, 12/17, 10, 15 |
List of subcortical regions belonging to the PD-ICA network and their peak z-scores. (BA: Brodmann area, na: not applicable, BNST: bed nucleus of the stria terminalis, ICA: independent component analysis, PD: Parkinson's disease).