Table 1. Sample information for all coeliac individuals and controls sequenced in this study.
Characteristic | Median or n | % † | Range | ||||
---|---|---|---|---|---|---|---|
Coeliac individuals | anti-CD3/CD28 | PMA | Unstimulated | ||||
Age, n 15 | 57.0 | 22–75 | 15 | 14 | 13 | ||
Females/Males, n 15 | 11/4 | 73.3/26.7 | |||||
Diagnosis age, n 15 | 39.0 | 0.5–70 | |||||
Diagnosis by age range, n 15 | < 18 years | 5 | 33.3 | ||||
≥18–35 years | 2 | 13.3 | |||||
>35–55 years | 5 | 33.3 | |||||
>55 | 3 | 20.0 | |||||
Clinical presentation at diagnosis *, n 12 | Classical CD | 9 | 75.0 | ||||
Non-classical CD | 2 | 16.7 | |||||
Subclinical CD | 1 | 8.3 | |||||
Family history of coeliac disease, n 15 | Yes | 5 | 33.3 | ||||
No | 10 | 66.7 | |||||
Family history of other autoimmune disease, n 15 | Yes | 5 | 33.3 | ||||
No | 10 | 66.7 | |||||
Presence of other autoimmune diseases, n 15 | Yes | 4 | 26.7 | ||||
No | 11 | 73.3 | |||||
Control individuals | |||||||
Age, n 11 | 50.0 | 40–70 | 11 | 11 | 10 | ||
Females/Males, n 11 | 7/4 | 63.6/36.3 |
* Clinical presentation at diagnosis was classified according to the Oslo definition of CD into; Classical, Non-classical and Subclinical
† Percentages provided are valid percentages