Fig. 5.

Effect of Li on the protein abundance of major renal Na⁺ transporters in the medulla of WT and KO mice. Top: representative Western blots of medullary homogenates. Blots were loaded with equal amounts of protein per lane, and band densities were normalized by probing for β-actin on the lower portion of the membrane (n = 5 mice/treatment per genotype). A representative β-actin blot is also shown. Bottom: bar graph summary of densitometry (means ± SE). Symbols above the bars show the results of a multiple-comparisons test after significant (P < 0.05) one-way ANOVA. ωSignificant difference from all other groups; τsignificant difference from both the WT-C and KO-C groups (both control treatments); δsignificant difference from the WT-C group only; λsignificant difference from the WT-Li group only.