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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Mol Carcinog. 2015 Apr 7;55(5):473–485. doi: 10.1002/mc.22295

Fig 1.

Fig 1

Effect of sfRON overexpression on BITC-induced apoptosis in MCF-7 cells. (A) Cell viability in MCF-7 and MCF-7/sfRON cultures after 12 h treatment with DMSO or increasing concentrations of BITC. Results are normalized against respective DMSO control for each cell type. (B) Flow histograms showing apoptotic fraction in control and BITC-treated cells (24 h treatment). (C) Quantitation of apoptotic cells (enrichment factor) relative to corresponding DMSO-treated control for each cell type is shown (mean ± S.D.; n = 3). Significantly different (P < 0.05) compared with *respective DMSO-treated control and #between MCF-7 and MCF-7/sfRON cells by one-way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison test. Similar results were obtained from replicate experiments.