Table 5.
GEE model of change in Serum PSA (ng/mL) from baseline to post intervention by study arm (N=74)
| Treatment | Time (Months) | N | 25% Quartile ng/mL | Median ng/mL | 75% Quartile ng/mL | Treatment effect on overall PSA change* | P value* |
|---|---|---|---|---|---|---|---|
| Placebo | 0 | 37 | 3.70 | 4.80 | 6.10 | −0.87 ng/ml (95%CI: −1.66, −0.09) | .029 |
| 6 | 36 | 3.55 | 5.45 | 6.30 | |||
| 12 | 28 | 3.65 | 4.90 | 6.15 | |||
| Polyphenon E | 0 | 36 | 3.50 | 4.45 | 5.60 | ||
| 6 | 35 | 2.80 | 3.70 | 5.20 | |||
| 12 | 29 | 2.80 | 3.50 | 5.10 |
*
The p-value and overall serum PSA change from GEE model accounts for all values at 6 and 12 months, and estimates an overall treatment effect during the study.