Table 2. Central tendency and variance values for iron status and inflammatory biomarkers in hemodialysis and peritoneal dialysis patients.
HD (n = 27) | PD (n = 27) | p-value* | |
---|---|---|---|
Iron Status Biomarker | |||
Hb [g/dL] | 9.0 (± 2.0) [3.8–16.5] | 9.9 (± 2.7) [6.0–16.5] | 0.17 |
Serum iron [μg/dL]† | 65 [24–148] | 65 [30–175] | 0.29 |
TIBC [μg/dL] | 282 [143–488] | 253 [154–340] | 0.53 |
Transferrin [ng/mL]† | 21 [7–63] | 28 [12–103] | 0.23 |
sTfR [mg/dL] | 3.4 [1.8–6.1] | 2.7 [0.3–7.1] | 0.14 |
Ferritin [ng/ML]† | 602 [193–4,113] | 458 [17–1,506] | 0.01 |
Hep-25 [nM] | 36 [2–131] | 43 [0.5–140] | 0.68 |
Inflammatory Biomarker | |||
WBC [103/μL] | 5.2 [2.7–14.1] | 6 [4–12] | 0.04 |
ESR [mm/h] | 97 [16–145] | 75 [2–125] | 0.03 |
CRP [mg/L] | [< 5–70] ǂ | [< 5–62] ǂ | NA |
IL-6 [pg/mL] | 7 [3–335] | 3 [1–13] | < 0.001 |
IL-10 [pg/mL] | 14 [5–690] | 6 [2.5–65] | < 0.001 |
TNF-α [pg/mL] | 6.5 [0–122] | [0–9] ǂ | < 0.001 |
HD, hemodialysis; PD, peritoneal dialysis; Hb, hemoglobin; TIBC, total iron binding capacity; sTfR, soluble transferrin receptor; Hep-25; hepcidin-25; WBC, white blood cell count; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IL-6, Interleukin-6; IL-10, Interleukin-10; TNF-α, tumor necrosis factor alpha; NA, not available.
Data are presented as means (± SD), or median and [minimum-maximum].
* P values determined according to t-test for normally distributed continuous variables, Mann-Whitney rank-sum tests for non-normally distributed continuous variables.
† Log transformed variables.
ǂ Only presented the range.