Table III.
Portions of Glycoforms Containing M5. Theoretical Values Were Calculated Based on the Assumption of Random Pairing. Observed Values Were Obtained from MS Analysis of intact mAb1
| M5:M5 | M5:G1F | M5:M3G1F | M5:G0F | M5:M3G0F | G0F:G0F | |
|---|---|---|---|---|---|---|
| Calculated relative | 0.62% | 1.12% | 0.11% | 5.29% | 0.18% | 45.43% |
| Calculated relative to the most abundant G0F:G0F | 1.36% | 2.46% | 0.24% | 11.64% | 0.40% | 100% |
| Observed relative to the most abundant G0F:G0F | 5.13% | ND | ND | 12.73% | ND | 100% |