Table 1.
Clinical and demographic characteristics.
| Case | Gender age |
Disease duration (years) |
H&Y | Pre-op medication (LEDD) |
Pre-op UPDRS |
DBS parameters for: left electrode (first row); right electrode (second row) |
Post-op medication (LEDD) |
Post-op UPDRS |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dopa-OFF | Dopa-ON | Dopa-OFF OFF-DBS |
Dopa-OFF ON-DBS |
Dopa-ON ON-DBS |
|||||||
| 1 | m, 66 | 11 | 3.5 | 2022 mg | 28 | 14 | 130 Hz, 1−, 4.0 V, 60 µs 130 Hz, 5−, 2.8 V, 60 µs |
1357 mg | 28 | 13 | N/A |
| 2 | m, 60 | 12 | 2 | 1049 mg | 26 | 9 | 240 Hz, 1+, 2−, 3−, 4.9 V, 120 µs 240 Hz, 5+, 6−, 7−, 4.4 V, 120 µs |
962 mg | N/A | N/A | N/A |
| 3 | f, 57 | 12 | 2.5 | 1422 mg | 20 | 9 | 130 Hz, 1−, 2−, 2.2 V, 60 µs 130 Hz, 5−, 6−, 2.2 V, 60 µs |
582 mg | N/A | 2 | 1 |
| 4 | f, 54 | 20 | 3 | 1241 mg | 22 | 11 | 130 Hz, 1−, 2−, 3.0 V, 60 µs 130 Hz, 5−, 6−, 2.6 V, 60 µs |
597 mg | 26 | 23 | 17 |
| 5 | f, 66 | 14 | 3 | 760 mg | 48 | 27 | 130 Hz, 1−, 2−, 3.9 V, 60 µs 130 Hz, 6−, 7−, 3.6 V, 90 µs |
938 mg | 44 | 25 | 19 |
| 6 | f, 69 | 12 | 3 | 806 mg | 47 | 42 | 200 Hz, 1−, 2−, 3.2 V, 60 µs 200 Hz, 5−, 6−, 3.0 V, 60 µs |
660 mg | 38 | 24 | 16 |
| 7 | m, 68 | 6 | 2 | 972 mg | 32 | 18 | 210 Hz, 1−, 2−, 3.2 V, 60 µs 210 Hz, 5−, 6−, 3.2 V, 60 µs |
549 mg | 33 | 12 | 10 |
| 8 | m, 56 | 20 | 3 | 1131 mg | 57 | 17 | 130 Hz, 1−, 3.2 V, 60 µs 130 Hz, 9−, 3.5 V, 60 µs |
635 mg | 57 | 25 | 10 |
| 9 | f, 68 | 13 | 4 | 1431 mg | 26 | 16 | 130 Hz, 2−, 1.9 V, 60 µs 130 Hz, 10−, 1.9 V, 60 µs |
497 mg | 44 | 27 | 19 |
| 10 | m, 57 | 15 | 3 | 1437 mg | 23 | 18 | 130 Hz, 1−, 2−, 3.0V, 60 µs 130 Hz, 9−, 10−, 3.0V, 60 µs |
943 mg | 52 | 32 | 27 |
| 11 | f, 59 | 11 | 3 | 397 mg | 26 | 12 | 200 Hz, 2−, 2.0 V, 60 µs 200 Hz, 10−, 2.5 V, 60 µs |
56 mg | 41 | 22 | 15 |
| 12 | f, 53 | 11 | 2 | 912 mg | 31 | 17 | 130 Hz, 1−, 2−, 2.3 V, 60 µs 130 Hz, 9−, 10−, 2.5 V, 60 µs |
180 mg | 37 | 18 | 14 |
Column “H&Y”: Hoehn & Yahr stages. Columns “Pre-op medication”, “Post-op medication”: levodopa equivalent daily doses (LEDD). Column “ DBS parameters”: stimulation frequency (Hz), active contacts, impulse amplitude (V), impulse width (µs) for left and right electrode, respectively. For the left electrode (first row), contact 0 was the most ventral and contact 3 was the most dorsal. For the right electrode (second row), contact 4 (or 8 in case of Activa PC stimulator) was the most ventral and contact 7 (or 11 in case of Activa PC stimulator) was the most dorsal.