Table 2.
Repeated measures ANOVA for effects of treatment and group on resting-state EEG.
| Repeated measures ANOVA | Factors |
Interaction of factors |
p-values of post-hoc analyses for: |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| df | f | p | df | f | p | Delta | Theta | Alpha | Beta | Gamma | |
| Relative power | |||||||||||
| DOPA-OFF vs. DOPA-ON | |||||||||||
| Frequency-Bands | 4,44 | 3.787 | .048 | 4,44 | 3.416 | .050 | .006 | .044 | |||
| Levodopa | 1,11 | 4.374 | .060 | ||||||||
| DOPA-OFF vs. OFF-DBS | |||||||||||
| Frequency-Bands | 4,44 | 6.547 | .005 | 4,44 | 8.779 | .003 | <.001 | .027 | .017 | ||
| Surgery | 1,11 | .297 | .597 | ||||||||
| DOPA-OFF vs. ON-DBS | |||||||||||
| Frequency-Bands | 4,44 | 3.831 | .039 | 4,44 | 13.115 | <.001 | .008 | <.001 | .002 | .006 | |
| Surgery | 1,11 | .086 | .775 | ||||||||
| DOPA-OFF vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 9.217 | <.001 | 4,88 | 1.178 | .317 | .015 | ||||
| Group | 1,22 | 7.139 | .014 | ||||||||
| DOPA-ON vs. OFF-DBS | |||||||||||
| Frequency-Bands | 4,44 | 9.435 | .001 | 4,44 | 3.845 | .034 | .018 | ||||
| Surgery | 1,11 | 3.511 | .088 | ||||||||
| DOPA-ON vs. ON-DBS | |||||||||||
| Frequency-Bands | 4,44 | 5.345 | .013 | 4,44 | 2.625 | .047 | .041 | .015 | |||
| Surgery | 1,11 | 3.543 | .087 | ||||||||
| DOPA-ON vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 12.319 | <.001 | 4,88 | .180 | .842 | |||||
| Group | 1,22 | 4.454 | .046 | ||||||||
| OFF-DBS vs. ON−DBS | |||||||||||
| Frequency-Bands | 4,44 | 9.527 | <.001 | 4,44 | .979 | .404 | |||||
| DBS | 1,11 | .348 | .567 | ||||||||
| OFF-DBS vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 22.819 | <.001 | 4,88 | 3.335 | .014 | .037 | .049 | |||
| Group | 1,22 | 8.709 | .007 | ||||||||
| ON-DBS vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 12.574 | <.001 | 4,88 | 1.640 | .195 | .034 | ||||
| Group | 1,22 | 6.414 | .019 | ||||||||
| Absolute power | |||||||||||
| DOPA-OFF vs. DOPA-ON | |||||||||||
| Frequency-Bands | 4,44 | 29.383 | <.001 | 4,44 | 3.423 | .053 | .016 | ||||
| Levodopa | 1,11 | .600 | .455 | ||||||||
| DOPA-OFF vs. OFF-DBS | |||||||||||
| Frequency-Bands | 4,44 | 43.843 | <.001 | 4,44 | 8.625 | .005 | .013 | .003 | .037 | ||
| Surgery | 1,11 | .584 | .461 | ||||||||
| DOPA-OFF vs. ON-DBS | |||||||||||
| Frequency-Bands | 4,44 | 30.879 | <.001 | 4,44 | 14.752 | <.001 | .008 | .008 | |||
| Surgery | 1,11 | 2.391 | .150 | ||||||||
| DOPA-OFF vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 71.830 | <.001 | 4,88 | 1.122 | .335 | .050 | .030 | .002 | .006 | .003 |
| Group | 1,22 | 18.627 | <.001 | ||||||||
| DOPA-ON vs. OFF-DBS | |||||||||||
| Frequency-Bands | 4,44 | 70.890 | <.001 | 4,44 | 3.535 | .049 | .038 | ||||
| Surgery | 1,11 | .045 | .836 | ||||||||
| DOPA-ON vs. ON-DBS | |||||||||||
| Frequency-Bands | 4,44 | 49.447 | <.001 | 4,44 | 2.492 | .105 | .002 | .020 | |||
| Surgery | 1,11 | 11.963 | .005 | ||||||||
| DOPA-ON vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 122.296 | <.001 | 4,88 | .192 | .837 | <.001 | .001 | <.001 | .010 | .005 |
| Group | 1,22 | 24.134 | <.001 | ||||||||
| OFF-DBS vs. ON-DBS | |||||||||||
| Frequency-Bands | 4,44 | 64.007 | <.001 | 4,44 | 1.108 | .350 | .039 | .025 | |||
| DBS | 1,11 | 4.339 | .061 | ||||||||
| OFF-DBS vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 176.203 | <.001 | 4,88 | 3.035 | .021 | .002 | <.001 | <.001 | .021 | .018 |
| Group | 1,22 | 20.167 | <.001 | ||||||||
| ON-DBS vs. controls | |||||||||||
| Frequency-Bands | 4,88 | 120.963 | <.001 | 4,88 | 1.423 | .249 | .026 | 0.009 | .022 | .044 | |
| Group | 1,22 | 9.359 | .006 | ||||||||
The reported values are degrees of freedom (df), F- and p-values for all the performed repeated measures ANOVA for both relative and absolute power changes. The within-subjects factors are Frequency-Bands (delta, theta, alpha, beta, gamma) and Treatment (Levodopa, Surgery, DBS). The between-subjects factor is Group (patients vs. controls). Results of the repeated measures ANOVA with p values still significant after Bonferroni corrections for the 20 separate ANOVAs are highlighted in bold (i.e., p < 0.0025), while results with p-values between ≥0.05 and ≤0.06 are reported in underlined font. If significant effects of factor Treatment or significant interactions between factor Treatment and factor Frequency-Bands were found in the ANOVA, post-hoc p-values for t-test comparisons between single frequency bands are reported. For post-hoc tests, p-values still significant after Bonferroni corrections are reported in bold (i.e., p < 0.01).