Table 4. Genetic polymorphism of metabolic enzymes in WBC counts as revealed by RFLP.

Polymorphism	Number (%)	WBC±SD (×109)	Beta	t	P
GSTM1
Present	215 (55.8)	5.75±1.67
Null	170 (44.2)	5.43±1.45	−0.11	−2.18	0.030
GSTT1
Present	188 (48.8)	5.81±1.68
Null	197 (51.2)	5.42±1.45	−0.10	−2.01	0.045
rs 1695
AA	206 (53.5)	5.67±1.60
AG	158 (41.0)	5.58±1.56	−0.04	−0.80	0.425
GG	21 (5.5)	5.24±1.48	−0.06	−1.11	0.265
GG+AG	179 (46.5)	5.54±1.55	−0.05	−1.03	0.305
rs3813867
GG	262 (68.1)	5.74±1.69
GC	111 (28.8)	5.36±1.30	−0.12	−2.45	0.014
CC	12 (3.1)	5.15±1.25	−0.04	−0.83	0.410
CC+GC	123 (31.9)	5.34±1.29	−0.13	−2.53	0.012
rs2031920
CC	258 (67.0)	5.75±1.63
CT	113 (29.4)	5.35±1.43	−0.12	−2.33	0.020
TT	14 (3.6)	5.04±1.44	−0.07	−1.43	0.153
TT+CT	127 (33.0)	5.32±1.43	−0.13	−2.56	0.011
rs6413432
TT	242 (62.9)	5.62±1.56
TA	123 (31.9)	5.60±1.64	−0.01	−0.14	0.893
AA	20 (5.2)	5.58±1.55	0	0	1
TA+AA	143 (37.1)	5.61±1.58	−0.01	0.12	0.90
rs1051740a
TT	92 (25.8)	5.54±1.54
TC	190 (53.2)	5.58±1.58	0.04	0.66	0.508
CC	75 (21.0)	5.78±1.63	0.08	1.29	0.197
TC/CC	265 (74.2)	5.63±1.59	0.05	0.97	0.331
rs2234922
AA	291 (75.6)	5.60±1.49
AG	90 (23.4)	5.64±1.88	0.02	0.33	0.742
GG	4 (1.0)	5.35±1.07	−0.01	−0.12	0.910
AG/GG	94 (24.4)	5.63±1.85	0.02	0.30	0.774
mEH 3, 4
Slow	263 (23.4)	5.64±1.60
Medium	83(1.0)	5.62±1.56	−0.12	−0.60	0.547
Fast	11 (24.4)	4.85±1.21	−0.70	−1.39	0.166

^a Data missing due to failure in DNA amplification.

Linear-regression analysis after adjusting gender, smoking, drinking. and age.