Skip to main content
. 2015 Mar;21(3):232–240. doi: 10.1179/2049396714Y.0000000091

Table 6. Associations between diplotypes of CYP2E1, mEH, and GSTM1/T1 and WBC counts.

Diplotypes N (%) WBC (×109) Beta t P
CYP2E1 rs3813867, rs2031920, rs6413432
GCT/GCT 182 5.67±1.59
GCT/GCA 49 6.14±1.89 0.47 1.88 0.061
GCT/GTT 19 5.18±1.93 −0.39 −1.02 0.308
GCT/CCA 11 5.03±1.27 −0.69 −1.42 0.156
GCT/CTT 32 5.66±1.19 −0.03 −0.10 0.921
GCT/CTA 57 5.29±1.40 −0.36 −1.54 0.125
GCA/GCA 7 6.41±1.54 0.76 1.25 0.211
CTA/CTA 5 4.56±0.95 −0.84 −1.19 0.234
All others 23 5.42±1.32 −0.27 −0.79 0.430
mEH rs1051740, rs2234922
TA/TA 81 5.63±1.56
TA/TC 11 4.85±1.21 −0.28 −0.55 0.582
TA/CA 45 5.74±1.41 0.26 0.87 0.384
TA/CC 29 5.84±1.98 0.19 0.55 0.584
CA/CA 148 5.54±1.43 0.09 0.40 0.693
CA/CC 40 5.73±2.08 0.18 0.61 0.542
All others 31 5.61±1.57 0.17 0.53 0.598
GSTM1 GSTT1
TM1+ TT1+ 105 5.96±1.77
TM1−TT1+ 110 5.56±1.55 −0.43 −1.91 0.057
TM1+TT1− 83 5.63±1.58 −0.40 −1.91 0.057
TM1−TT1− 87 5.24±1.30 −0.66 −2.97 0.005