Table 6. Associations between diplotypes of CYP2E1, mEH, and GSTM1/T1 and WBC counts.
Diplotypes | N (%) | WBC (×109) | Beta | t | P |
CYP2E1 rs3813867, rs2031920, rs6413432 | |||||
GCT/GCT | 182 | 5.67±1.59 | |||
GCT/GCA | 49 | 6.14±1.89 | 0.47 | 1.88 | 0.061 |
GCT/GTT | 19 | 5.18±1.93 | −0.39 | −1.02 | 0.308 |
GCT/CCA | 11 | 5.03±1.27 | −0.69 | −1.42 | 0.156 |
GCT/CTT | 32 | 5.66±1.19 | −0.03 | −0.10 | 0.921 |
GCT/CTA | 57 | 5.29±1.40 | −0.36 | −1.54 | 0.125 |
GCA/GCA | 7 | 6.41±1.54 | 0.76 | 1.25 | 0.211 |
CTA/CTA | 5 | 4.56±0.95 | −0.84 | −1.19 | 0.234 |
All others | 23 | 5.42±1.32 | −0.27 | −0.79 | 0.430 |
mEH rs1051740, rs2234922 | |||||
TA/TA | 81 | 5.63±1.56 | |||
TA/TC | 11 | 4.85±1.21 | −0.28 | −0.55 | 0.582 |
TA/CA | 45 | 5.74±1.41 | 0.26 | 0.87 | 0.384 |
TA/CC | 29 | 5.84±1.98 | 0.19 | 0.55 | 0.584 |
CA/CA | 148 | 5.54±1.43 | 0.09 | 0.40 | 0.693 |
CA/CC | 40 | 5.73±2.08 | 0.18 | 0.61 | 0.542 |
All others | 31 | 5.61±1.57 | 0.17 | 0.53 | 0.598 |
GSTM1 GSTT1 | |||||
TM1+ TT1+ | 105 | 5.96±1.77 | |||
TM1−TT1+ | 110 | 5.56±1.55 | −0.43 | −1.91 | 0.057 |
TM1+TT1− | 83 | 5.63±1.58 | −0.40 | −1.91 | 0.057 |
TM1−TT1− | 87 | 5.24±1.30 | −0.66 | −2.97 | 0.005 |