Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 20;14(10):2644–2660. doi: 10.1074/mcp.M115.049726

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Fig. 4. — AI-NETD outperforms NETD on a global scale. (A) The distribution of precursors selected for NETD or AI-NETD in a given run show roughly equivalent populations of peptides to fragment. (B) Using the PSMs generated from the runs shown in (A), peptide sequence coverage is plotted as a function of precursor m/z. AI-NETD increases the number of peptides identified, extends the m/z range that can generate successful PSMs, and provides overall higher peptide sequence coverage at given m/z values. (C) The combination of these improvements with AI-NETD at the peptide level translates to benefits at the protein level as well. AI-NETD characterized 1,106 proteins to NETD's 674. Beyond this, for proteins detected with both methods, AI-NETD overwhelmingly enhanced protein sequence coverage, by more than 50% in some cases.