Table 2.

Physiological parameters of control and RAGE^−/− mice 10 min before and 10 min after MCAO

Parameter	RAGE+/+		RAGE−/−
	Before MCAO (n = 6)	After MCAO (n = 6)	Before MCAO (n = 6)	After MCAO (n = 6)
MABP (mm Hg)	62.0 ± 2.4	56.8 ± 5.6	60.0 ± 7.3	56.2 ± 5.3
Heart rate (per min)	274.7 ± 34.1	275.6 ± 19.6	276.0 ± 30.6	266.0 ± 25.6
Glucose (mg/dl)	229.3 ± 128.6	266.6 ± 168.4	220.7 ± 42.8	227.7 ± 69.2
Arterial pH	7.2 ± 0.09	7.13 ± 0.06	7.3 ± 0.06	7.21 ± 0.06
Arterial pO2 (mm Hg)	107.7 ± 11.7	93.9 ± 5.7	99.7 ± 12.6	86.6 ± 16.9
Arterial pCO2 (mm Hg)	41.1 ± 11.2	47.2 ± 4.2	42.7 ± 5.1	43.6 ± 6.5
Base excess	−10.7 ± 2.5	−12.2 ± 4.5	−7.3 ± 4.3	−10.3 ± 2.6
Hb (g/l)	15.1 ± 1.8	13.2 ± 1.6	16.6 ± 0.9	15.0 ± 1.8
Laser doppler (% before MCAO)		15.7 ± 4.7		12.3 ± 4.2
Body weight	31.5 ± 3.0		28.0 ± 2.6

There was no significant difference between the genotypes (t test). MABP, Mean arterial blood pressure.