Table 1. Characteristics of the study population categorized by CHDs and controls.
| Characteristics | CHDs (N = 66) | Controls (N = 58) | Statistical parameter | Pvalue |
|---|---|---|---|---|
| Age (years) | 62.20 ± 8.95 | 55.93 ± 8.68 | −3.946 | 0.000 |
| Gender (F/M) | 12/54 | 21/37 | 5.136 | 0.023 |
| TCH | 4.75 ± 1.04 | 4.64 ± 0.99 | −0.606 | 0.546 |
| HDL-C | 1.35 ± 0.33 | 1.50 ± 0.34 | 2.354 | 0.020 |
| LDL-C | 2.93 ± 0.91 | 2.76 ± 0.85 | −1.045 | 0.298 |
| FBG | 5.44(4.88 ~ 6.34) | 5.04(4.71 ~ 5.50) | 1266.00 | 0.006 |
| CR | 74.10 ± 15.87 | 68.56 ± 11.62 | −2.161 | 0.033 |
| Gensini scores | 35.50(16.75 ~ 64.50) | 0.00(0.00 ~ 2.00) | 51.000 | 0.000 |
| miR-433 | 0.60(0.31 ~ 1.15) | 0.62(0.37 ~ 1.13) | 1868.500 | 0.820 |
| miR-1 | 1.56(0.49 ~ 3.18) | 0.87(0.44 ~ 2.18) | 1651.500 | 0.189 |
| miR-122 | 0.48(0.12 ~ 1.42) | 0.31(0.10 ~ 0.8) | 1733.000 | 0.366 |
| miR-133a | 0.43(0.19 ~ 0.9) | 0.35(0.23 ~ 0.79) | 1810.000 | 0.602 |
| miR-145 | 0.10(0.04 ~ 0.17) | 0.08(0.04 ~ 0.18) | 1829.000 | 0.670 |
| miR-214 | 0.18(0.04 ~ 1) | 0.13(0.03 ~ 0.49) | 1698.500 | 0.280 |
| miR-21 | 0.61(0.38 ~ 1.01) | 0.64(0.42 ~ 1.09) | 1763.500 | 0.451 |
| miR-25 | 0.02(0.01 ~ 0.08) | 0.02(0.01 ~ 0.08) | 1851.000 | 0.747 |
| miR-20a | 0.38 ± 0.26 | 0.39 ± 0.33 | 0.028 | 0.978 |
| miR-106a | 2.41(1.51 ~ 3.99) | 2.69(1.79 ~ 4.31) | 1757.000 | 0.432 |
| miR-92a | 0.19(0.04 ~ 0.78) | 0.20(0.08 ~ 1.16) | 1707.500 | 0.301 |
| miR-130a | 54.35(29.32 ~ 111.82) | 61.82(35.26 ~ 107.49) | 1880.500 | 0.867 |
| miR-155 | 197.19(102.36 ~ 371.59) | 201.56(118.86 ~ 322.18) | 1908.500 | 0.978 |
| miR-208b | 1.13(0.63 ~ 4.13) | 1.02(0.6 ~ 3.56) | 1791.500 | 0.540b |
| miR-499 | 3.5(2.19 ~ 8.62) | 3.09(2.03 ~ 6.66) | 1739.500 | 0.382 |
| miR-485-3p | 1.79(0.97 ~ 5.53) | 1.54(0.76 ~ 3.35) | 1708.000 | 0.302 |
| miR-133b | 0.14(0.06 ~ 0.23) | 0.17(0.11 ~ 0.22) | 1662.000 | 0.207 |
| miR-221 | 0.4(0.19 ~ 0.82) | 0.55(0.22 ~ 0.92) | 1740.000 | 0.384 |
| miR-208a | 1.13(0.63 ~ 4.13) | 1.87(1.19 ~ 3.78) | 1632.500 | 0.159 |
| miR-125b | 0.14 ± 0.09 | 0.18 ± 0.10 | 1.938 | 0.055 |
Data are summarized by either mean ± standard deviation or 50th (25th/75th) percentiles for continuous variables and N1/N2 for binary variables. CHD, coronary heart disease; TCH, total cholesterol; HDL-C, fasting high-density lipoprotein cholesterol; LDL-C, fasting low-density lipoprotein cholesterol; TG, triglyceride; FBG, fasting blood glucose; CR, creatinine. The value of each miRNAs means the relative mount calculated by 2−Δct method.