Table 4. Receiver operating characteristic curve analyses in subjects with CHD and controls.
Variables | AUC(95% CI) | P value |
---|---|---|
Age (years) | 0.695(0.601 ~ 0.788) | 0.000 |
TCH | 0.515(0.411 ~ 0.619) | 0.780 |
HDL-C | 0.354(0.255 ~ 0.454) | 0.006 |
LDL-C | 0.542(0.438 ~ 0.645) | 0.432 |
FBG | 0.647(0.549 ~ 0.745) | 0.006 |
CR | 0.622(0.522 ~ 0.723) | 0.021 |
miR-433 | 0.488(0.386 ~ 0.590) | 0.820 |
miR-1 | 0.569(0.467 ~ 0.670) | 0.189 |
miR-122 | 0.547(0.445 ~ 0.649) | 0.366 |
miR-133a | 0.527(0.425 ~ 0.630) | 0.602 |
miR-145 | 0.522(0.419 ~ 0.625) | 0.670 |
miR-214 | 0.556(0.455 ~ 0.658) | 0.281 |
miR-21 | 0.461(0.359 ~ 0.562) | 0.451 |
miR-25 | 0.484(0.381 ~ 0.586) | 0.752 |
miR-20a | 0.522(0.419 ~ 0.625) | 0.674 |
miR-106a | 0.459(0.357 ~ 0.561) | 0.432 |
miR-92a | 0.446(0.344 ~ 0.548) | 0.301 |
miR-130a | 0.491(0.388 ~ 0.594) | 0.867 |
miR-155 | 0.501(0.399 ~ 0.604) | 0.978 |
miR-208b | 0.532(0.430 ~ 0.634) | 0.540 |
miR-499 | 0.546(0.444 ~ 0.674) | 0.382 |
miR-485-3p | 0.554(0.452 ~ 0.656) | 0.302 |
miR-133b | 0.434(0.333 ~ 0.536) | 0.207 |
miR-221 | 0.455(0.353 ~ 0.556) | 0.384 |
miR-208a | 0.574(0.430 ~ 0.675) | 0.159 |
miR-125b | 0.405(0.305 ~ 0.506) | 0.070 |
CI, confidence interval; AUC, area under the receiver operating characteristic curve; TCH, total cholesterol; HDL-C, fasting high-density lipoprotein cholesterol; LDL-C, fasting low-density lipoprotein cholesterol; TG, triglyceride; FBG, fasting blood glucose; CR, creatinine. The value of each miRNAs means the relative mount calculated by 2−Δct method.
AUC < 0.5 indicates the levels in patients with CHD lower than in controls.
AUC > 0.5 indicates the levels in patients with CHD higher than in controls.