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. 2015 Sep 4;5:45. doi: 10.1186/s13550-015-0124-0

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© Tahara et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Time activity curves of injected [¹¹C]AZT or [¹¹C]d4T in the tissues of tumor-bearing mice. (a) Time changes of activity of [¹¹C]AZT (expressed as Closed) or [¹¹C]d4T (expressed as Opened) in C6 (expressed as Diamond) and HeLa (expressed as Square) tumor tissues over 3600 s. Statistical analysis of [¹¹C]AZT injected mice vs [¹¹C]d4T injected mice by RM two-way ANOVA indicates a significant difference, ***P < 0.001. (b) The uptake of [¹¹C]AZT by tumor and several normal tissues over 3600 s after injection into C6 or HeLa tumor-bearing mice (n = 3 per group). The data were averaged from 3 mice and activity is indicated as the SUV