Table 3.

Haematological and clinical biochemical results before and after weight loss

Parameter	Before weight loss	After weight loss	Reference range	P value
Red blood cells ×10 12 /L	6.9 (5.3-8.1), 0, 2	6.9 (5.3-8.0), 0, 1	5.5-8.2	0.652
Haemoglobin g/L	16.0 (12.4-18.8), 0, 2	16.0 (11.3-17.9), 0, 3	12.6-19.4	0.690
Haematocrit L/L	0.48 (0.36-0.55), 0, 0	0.47 (0.35-0.54), 0, 0	0.35-0.55	0.880
Platelets ×10 9 /L	276 (13–385), 0, 2	266 (140–444), 0, 0	80-560	0.473
White blood cells ×10 9 /L	10.4 (5.1-18.7), 2, 1	8.2 (4.6-14.0), 0, 5	6.7-18.3	<0.001
Sodium mmol/L	147 (142–153), 0, 0	146 (140–151), 0, 0	140-153	0.155
Potassium mmol/L	4.6 (3.8-6.0), 1, 0	4.2 (3.7-6.0), 1, 1	3.8-5.3	0.199
Calcium mmol/L	2.8 (2.3-3.1), 3, 0	2.6 (1.8-2.9), 0, 2	2.20-2.90	<0.001
Phosphate mmol/L	1.0 (0.5-2.2), 1, 3	1.0 (0.5-1.5), 0, 5	0.8-2.0	0.058
Alanine aminotransferase U/L	44 (18–293), 13, 0	49 (18–238), 13, 0	7-50	0.893
Alkaline phosphatase U/L	74 (23–392), 11, 0	54 (26–295), 8, 0	0-100	0.065
Albumin g/L	32 (28–36), 1, 0	29 (25–36), 2, 0	25-35	<0.001
Cholesterol mmol/L	6.1 (4.1-7.9), 5, 0	5.4 (3.0-7.3), 1, 2	3.5-7.0	0.040
Creatinine μmol/L	84 (44–123), 2, 0	72 (46–114), 1, 0	20-110	0.033
Globulins g/L	31 (22–44), 2, 0	27 (23–42), 1, 0	22-40	0.012
Glucose mmol/L	5.1 (3.3-5.9), 5, 1	5.2 (3.0-7.4), 5, 1	3.5-5.5	0.210
Urea mmol/L	4.6 (1.8-7.6), 4, 5	5.2 (2.4-8.9), 1, 1	3.5-7.0	0.047
Free thyroxine pmol/L	21.0 (7.0-42.9), 2, 0	20.0 (8.4-34.0), 0, 0	6.6-40.0	0.562

Data are expressed as median (range), number of results above reference range, and number below reference range

P values quoted for Wilcoxon signed ranks test comparing pre- and post-weight-loss measurements. In the dogs, before and after weight loss, with low platelet counts, platelet clumps were identified on a blood smear suggesting that actual numbers were normal