Table 7.
Treatment mg/kg |
Edema volume (ml)/ Percent edema inhibition | ||||
---|---|---|---|---|---|
0 h | 1 h | 2 h | 3 h | 4 h | |
DMSO (2 ml) | 0.506 ± 0.046 | 0.776 ± 0.045 | 0.710 ± 0.021 | 0.671 ± 0.017 | 0.600 ± 0.021 |
DIC (10) | 0.551 ± 0.056 | 0.706 ± 0.056 | 0.640 ± 0.049 | 0.613 ± 0.049 | 0.586 ± 0.056 |
42.862 ± 5.614ab | 56.903 ± 8.443ab | 69.975 ± 5.730a | 78.823 ± 6.395a | ||
EDH (300) | 0.548 ± 0.022 | 0.685 ± 0.033 | 0.630 ± 0.021 | 0.615 ± 0.018 | 0.600 ± 0.023 |
49.652 ± 7.649a | 60.171 ± 3.690a | 67.524 ± 8.004a | 68.660 ± 10.502a | ||
EDA (300) | 0.548 ± 0.035 | 0.751 ± 0.027 | 0.696 ± 0.030 | 0.683 ± 0.032 | 0.651 ± 0.031 |
24.960 ± 7.283c | 27.492 ± 5.730d | 34.028 ± 9.170c | 37.156 ± 6.297c | ||
EDE (300) | 0.560 ± 0.037 | 0.730 ± 0.016 | 0.676 ± 0.037 | 0.651 ± 0.039 | 0.640 ± 0.026 |
37.307 ± 8.113abc | 43.014 ± 12.271bc | 55.269 ± 7.215ab | 51.384 ± 8.623b | ||
EDEW (300) | 0.520 ± 0.046 | 0.705 ± 0.045 | 0.643 ± 0.030 | 0.633 ± 0.044 | 0.608 ± 0.039 |
31.752 ± 3.883bc | 39.746 ± 10.125cd | 44.648 ± 9.127bc | 46.302 ± 8.975bc | ||
EDM (300) | 0.545 ± 0.032 | 0.738 ± 0.026 | 0.683 ± 0.031 | 0.676 ± 0.026 | 0.653 ± 0.039 |
28.665 ± 11.396c | 32.394 ± 8.443cd | 35.662 ± 12.938c | 34.107 ± 8.975c |
EDH E. dracunculoides n-hexane extract, EDA E. dracunculoides aqueous extract, EDE E. dracunculoides ethyl acetate, EDEW E. dracunculoides ethyl acetate + water extract, EDM E. dracunculoides methanol extract (EDM), DIC diclofenac sodium
Data values shown represent mean ± SD (n = 6). Means with different superscript (a-d) letters in the column are significantly (P < 0.05) different from one another