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. 2015 Oct 7;15:352. doi: 10.1186/s12906-015-0869-z

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© Wang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — QSYQ inhibited expressions of COXs. a Western blot showed that expressions of COX1 and COX2 in cardiac tissues were significantly up-regulated in the model group compared with those in the sham group. In the aspirin and QSYQ-treated groups, expressions of COX1 and COX2 were all down-regulated compared with those in the model group. The inhibitory effect of QSYQ on COXs was milder than that of aspirin. b Expression of cardiac PGE2 in the model heart tissues was up-regulated as compared with that in the sham group and treatments with aspirin and QSYQ down-regulated expression of PGE2 towards basal level. Figure (c) and (d) were the relative quantitative illustrations of expressions of COX1 and COX2 in different groups (*P < 0.05, **P < 0.01, ***P < 0.001, other groups vs. model group, n = 8)