Table 7.

Multivariate Analysis of Factors Associated With Cortical Opacity Incidence and Progression

Characteristic	Cortical Incidence (n analyzed = 2485)	Cortical Progression (n analyzed = 859)
	Odds Ratio (95% Confidence Interval)	Odds Ratio (95% Confidence Interval)
Age (per year increase)	1.03 (0.97–1.08)	1.00 (0.96–1.04)
Female/Male	1.93 (1.18–3.16)	1.40 (0.88–2.22)
African-Americans/Caucasians	1.97 (1.17–3.32)	1.85 (1.28–2.68)
High school or more	0.86 (0.53–1.40)	1.12 (0.76–1.66)
Past steroid use	1.43 (0.57–3.50)	0.70 (0.36–1.35)
Smoking status
Never	1.00	1.00
Past	1.08 (0.63–1.85)	1.38 (0.90–2.12)
Current	1.11 (0.55–2.23)	1.89 (1.03–3.47)
Alcohol status
Never	1.00	1.00
Past	1.45 (0.74–2.86)	0.61 (0.37–1.00)
Current	1.33 (0.70–2.49)	0.63 (0.39–1.01)
History of hypertension	0.84 (0.53–1.34)	0.74 (0.50–1.10)
Diabetes	1.80 (1.06–3.04)	0.90 (0.59–1.38)
Body Mass Index >30	0.90 (0.53–1.51)	1.08 (0.72–1.62)
Average annual Ultraviolet-B exposure (1/10 Maryland sun year)	3.72 (1.04–13.1)	2.33 (0.78–6.97)

Caucasians are used as reference group. SE values have been corrected to account for the correlation between eyes of the same subject. Statistically significant results in bold.