Table 2.

Refinement statistics.

	CPV4 Cell 1	CPV4 Cell 2	CPV5	CPV5 SeMet	CPV14	CPV15	CPV17 room temp	CPV17 frozen	CPV18	CPV19	CPV20	CPV1Δ	CPV4Δ
Resolution (Å)	29.4–1.72	28.0–2.00	51.2–1.61	36.1–2.07	32.4–1.91	42.0–1.82	28.30–1.75	74.16–2.20	72.7–1.48	41.9–1.51	51.7–1.83	42.4–1.88	27.9–1.71
No. of reflections	17233	11542	23282	10889	11856	16408	20122	9376	30414	20976	16323	15016	19908
Rwork/Rfree	0.118/0.166	0.175/0.239	0.159/0.197	0.169/0.228	0.141/0.184	0.162/0.220	0.122/0.154	0.147/0.199	0.130/0.148	0.166/0.228	0.157/0.190	0.189/0.251	0.185/0.216
No. of atoms
Protein	2028	1637	2002	2002	2022	1952	1914	1907	2001	2058	1979	1686	1628
Ligand (#NTPs)	0	0	0	1 (0)	32 (1)	89 (2)	32 (1)	32 (1)	63 (2)	32 (1)	29 (1)	0	0
Water	176	92	166	112	165	176	174	146	246	235	161	101	136
B-factors
Protein	13.2	22.8	12.6	14.2	12.7	16.7	23.7	22.5	8.4	14.3	21.4	36.0	26.9
Ligand	–	–	–	51.0	49.8	28.4	34.4	50.0	31.0	18.5	47.1	–	–
Water	20.1	28.4	19.6	16.3	17.3	21.8	32.7	32.2	16.8	20.8	25.6	36.1	37.0
rmsd
Bond lengths (Å)	0.006	0.006	0.008	0.006	0.006	0.007	0.010	0.013	0.005	0.007	0.003	0.003	0.003
Bond angles (°)	1.09	0.98	1.19	1.02	1.08	1.28	1.39	1.675	1.146	1.12	0.83	0.79	0.74
rmsZ
Bond length	0.39	0.34	0.41	0.32	0.40	0.37	0.50	0.68	0.30	0.38	0.23	0.26	0.23
Bond angles	0.56	0.52	0.58	0.49	0.57	0.53	0.63	0.82	0.52	0.53	0.43	0.44	0.42
Model quality (Ramachandran plot)
Most favoured (%)	98.8	98.0	98.0	97.6	96.0	96.6	97.9	97.4	97.6	97.6	97.9	97.1	98.0
Allowed (%)	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0
PDB ID code	5A8S	5A8T	5A8U	5A8V	5A96	5A98	4S1L	4S1K	5A9P	5A99	5A9A	5A9B	5A9C