Table 4.

Effects of oral administration of the MYCI mixture on intestinal mucosal morphology of newborn piglets after an oral administration of PEDV^a)

	Not challenged			Challenged (Chal)			P-value
	CONb) (n = 5)	MYCI (n = 5)	SEM	CON (n = 6)	MYCI (n = 6)	SEM	Chal	MYCI	C × M
Duodenum
VHb), μm	443	482	38.3	409	471	31.7	0.050	<0.001	0.023
CDb), μm	171	171	10.7	183	173	16.1	0.183	0.255	0.533
VH:CD	2.65	2.72	0.163	2.31	2.74	0.149	0.590	0.392	0.002
Jejunum
VH, μm	144	151	11.7	129	154	13.3	0.156	0.002	0.030
CD, μm	157	137	13.0	170	138	9.5	0.040	<0.001	0.001
VH:CD	0.98	1.18	0.166	0.89	1.23	0.155	0.946	0.377	0.013
Ilium
VH, μm	166	182	13.3	161	184	10.1	0.648	<0.001	0.015
CD, μm	165	166	15.9	160	142	11.0	0.001	0.027	0.048
VH:CD	1.12	1.16	0.156	1.01	1.32	0.170	0.933	0.547	0.058

^aNewborn piglets received an oral challenge with 3 × 10^3.5 TCID₅₀ of PEDV in PBS or PBS only and daily administration 60 mg of the MYCI mixture suspended in milk replacer or the vehicle for 7 days

^bCON, control; VH, villus height; CD, crypt depth