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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Alcohol Clin Exp Res. 2015 Aug;39(8):1360–1372. doi: 10.1111/acer.12772

Table 2. Enzymes examined that are associated with ethanol metabolism and their function.

Gene Function Refs
Aldh2 Metabolizes AcH to acetate Seitz & Becker, 2007; Black et al, 2009; Singh et al., 2013
Aldh1a3 Metabolizes retinaldehyde to retinoic acid Seitz & Becker, 2007; Black et al, 2009; Singh et al., 2013
Adh1 Metabolizes EtOH to AcH Seitz & Becker, 2007; Jelski et al, 2006
Adh7 Metabolizes EtOH to AcH Seitz & Becker, 2007; Jelski et al, 2006
Cyp2e1 Metabolizes xenobiotics (EtOH to AcH) Seitz & Becker, 2007; Lu et al., 2011
Cyp2a5 Metabolizes drugs and toxins (i.e. nicotine) (Cyp2a6 is human orthologue) Seitz & Becker, 2007; Lu et al, 2011; Xu et al., 2002