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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Eur J Immunol. 2015 Jun 9;45(8):2312–2323. doi: 10.1002/eji.201545547

Figure 7. Cytokine production by B10, B6 and congenic DC-CD4 T cell cocultures stimulated with live eggs.

Figure 7

(A–D) Naïve CD4 T cells from B10, B6, B6.B10-4/117-143 and B6.B10-13/16-41 mice were cocultured with syngeneic BMDCs in the presence or absence of αCD3/CD28 coated beads and 200 eggs as described in Materials and Methods. (A) IL-1β, (B) IL-23, (C) IL-17 and (D) IL-5 levels in 4 day culture supernatants were measured by ELISA. Cytokine levels are expressed as means +/− SD of 3 individual samples within an experiment. Results shown are from one experiment representative of 2 (IL-1, IL-23, IL-5) or 3 (IL-17) with similar results. Statistically significant differences with respect to B6 were determined by the Student’s t test performed by Prism software. ** = p < 0.01, * = p < 0.05, otherwise not significant.