Table 2.

Single-Nucleotide Polymorphisms Showing Association With Posttraumatic Stress Disorder Symptoms in Interaction With the Level of Childhood Adversity

Chromosome	SNP	Size, base pair	Locus	Location	Position Relative to Gene	P Value for HWE	MAF	Allele	P Value
									Raw	Correcteda
5	rs2400707	148 205 052	ADRB2	5′-Flank	−1124	.919	0.438	G:A	1.02 × 10−5	.0448
5	rs2053044	148 205 372	ADRB2	5′-Flank	−804	>.99	0.439	G:A	1.37 × 10−5	.0575
5	rs1432622	148 203 762	ADRB2	5′-Flank	−2414	>.99	0.440	G:A	1.42 × 10−5	.0594
5	rs1432623	148 204 008	ADRB2	5′-Flank	−2168	>.99	0.440	A:G	1.42 × 10−5	.0594
5	rs11168068	148 204 121	ADRB2	5′-Flank	−2055	>.99	0.440	A:G	1.42 × 10−5	.0594
5	rs1042714	148 206 473	ADRB2	Nonsynonymous	E27Q	>.99	0.438	G:C	2.05 × 10−5	.0786
5	rs11168070	148 205 927	ADRB2	5′-Flank	−249	>.99	0.438	G:C	2.11 × 10−5	.0799
10	rs16914791	61 895 547	ANK3	Intron	−1416	.87	0.050	A:G	4.23 × 10−5	.1305
21	rs420121	31 146 608	GRIK1	Intron	−80 226	.95	0.392	T:C	1.01 × 10−4	.2383

Abbreviations: HWE, Hardy-Weinberg equilibrium; MAF, minor allele frequency; SNP, single-nucleotide polymorphism.

^aCorrected for multiple comparisons.