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. 2015 Oct 8;9(10):e0004137. doi: 10.1371/journal.pntd.0004137

Table 3. L. braziliensis parasite loads 1 detected in tissue samples from rodents with infections established by high or low dose initial inoculum.

Rodent/dose Tissue sample Pos/N tested mean Median (IQR) 2 range
High dose
N. lasiurus skin 8/8 3.6×102 52 (2–1006) 1–1.6×103
spleen 6/8 3.9×102 2 (0–1110) 0–2.8×103
liver 7/7 1.4×102 6 (6–632) 1–8.9×102
N. squamipes skin 7/7 1.5×103 56 (10–6263) 6–8.1×103
Spleen 6/6 3.2×102 11 (8–1641) 1.8×103
liver 7/7 1.6×102 9 (3–668) 3–8.8×102
R. rattus skin 1/9 0.3 0 (0–0) 0–3
spleen 1/9 2.6 0 (0–0) 0–2.3×101
liver 0/8 0 0 (0–0) 0–0
Low dose
N. lasiurus skin 8/9 1.3×101 8 (5–17) 0–4.6×101
spleen 9/9 3.4×101 2 (2–5) 1–2.9×102
liver 9/9 2.4×101 6 (2–51 1–1.3×102
N. squamipes skin 9/10 3.7×101 14 (5–43) 0–2.3×102
spleen 10/10 4.4×101 25 (9–61) 4–2.0×102
liver 10/10 9.0×101 10 (4–127) 4–6.4×102
R. rattus skin 1/8 0.9 0 (0–2) 0–7
spleen 1/9 0.1 0 (0–0) 0–1
liver 2/8 4.3 0 (0–17) 0–1.8×101

1 Leishmania copy numbers (loads) measured by qPCR were standardized to the number of host gene GAPDH copies.

2 IQR interquartile range