Table 3. Summary of Three-Way ANOVA results for genes examined in the nucleus accumbens and prefrontal cortex of impulsive and standard rats with and without a mTBI (F (p), bold text denotes significant effects).

	Gene	Sex Effect	Injury Effect	Cohort Effect	Sex x Injury	Sex x Cohort	Injury x Cohort	3-Way Interaction
	Comt	1.35 (.25)	12.39 (< .01)	0.18 (.68)	14.44 (< .01)	1.05 (.32)	3.19 (.09)	2.28 (.15)
	Drd2	10.72 (< .01)	2.25 (.15)	0.01 (.91)	1.29 (.27)	0.08 (.78)	0.52 (.47)	2.71 (.11)
	Drd3	0.92 (.35)	2.12 (.16)	7.03 (.01)	1.62 (.22)	1.31 (.26)	0.04 (.85)	5.02 (.03)
NAc	Drd4	0.37 (.55)	0.94 (.34)	0.20 (.66)	21.19 (< .01)	1.67 (.21)	0.53 (.47)	0.06 (.80)
	Maoa	21.87 (< .01)	9.03 (< .01)	3.09 (.09)	9.39 (< .01)	1.10 (.30)	4.79 (.04)	0.47 (.50)
	Sert	0.94 (.34)	0.18 (.67)	0.28 (.60)	0.47 (.50)	1.45 (.24)	0.05 (.84)	0.11 (.74)
	Tph1	0.00 (.99)	0.70 (.41)	0.50 (.49)	0.23 (.64)	3.41 (.07)	0.35 (.56)	5.59 (.02)
	Tph2	44.72 (< .01)	4.71 (.04)	4.60 (.04)	10.50 (< .01)	0.44 (.51)	10.3 (< .01)	0.04 (.84)
	Comt	0.09 (.77)	0.10 (.75)	0.61 (.44)	2.88 (.10)	3.54 (.07)	0.80 (.38)	0.03 (.87)
	Drd2	0.25 (.62)	0.33 (.57)	4.10 (.05)	8.58 (< .01)	3.50 (.07)	0.00 (.98)	1.52 (.23)
	Drd3	N/A
PFC	Drd4	0.43 (.52)	0.06 (.81)	1.78 (.20)	0.01 (.98)	8.56 (< .01)	0.01 (.91)	0.02 (.88)
	Maoa	0.06 (.80)	2.36 (.14)	2.08 (.16)	5.72 (.03)	35.2 (< .01)	1.13 (.29)	1.38 (.25)
	Sert	3.34 (.08)	0.08 (.78)	8.46 (< .01)	4.06 (.05)	0.01 (.98)	1.87 (.18)	1.06 (.32)
	Tph1	0.03 (.87)	1.76 (.19)	7.27 (.01)	0.17 (.69)	1.76 (.19)	1.96 (.18)	1.57 (.22)
	Tph2	6.25 (.01)	0.54 (.47)	5.94 (.02)	4.30 (.05)	11.7 (< .01)	0.05 (.82)	0.23 (.63)