. Author manuscript; available in PMC: 2015 Oct 8.

Published in final edited form as: Macromol Biosci. 2011 May 12;11(8):1041–1051. doi: 10.1002/mabi.201100019

Table 1.

Cytotoxicity of free 3-Cl-AHPC-OMe and PCL-b-PHPMA micelle-loaded 3-Cl-AHPC-OMe for different incubation times.

Formulation	IC₅₀^a) [μM] (mean ± SD)
	12 h	24 h	48 h	72 h
Free 3-Cl-AHPC-OMe	45.02 ± 6.47	28.52 ± 4.55	3.71 ± 1.09	1.71 ± 0.17
3-Cl-AHPC-OMe-loaded PCL-b-PHPMA micelles	–^b)	58.92 ± 10.94	6.78 ± 0.62	1.96 ± 0.23

^a)

Values are expressed as mean 50% inhibition concentration (IC₅₀) values with standard deviation (SD) calculated from 3 replicas (2 for the 72 h points);

^b)

Cytotoxicity was too low for IC₅₀ determination.