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. Author manuscript; available in PMC: 2015 Oct 8.
Published in final edited form as: Am J Med Genet A. 2015 Feb 23;0(4):744–751. doi: 10.1002/ajmg.a.36982

Figure 3.

Figure 3

A: Pathological examination of the explanted heart at age 36 weeks showing massive biventricular hypertrophy, thickened endocardium, and small ventricular cavities. B-D: Microscopic analysis depicting marked perivascular fibrosis and profound wall thickening of an arteriole (arrows). (e, g) Desmin staining, methylene blue stained semi-thin section (MB), and electron microscopy demonstrating disarray of myofibers and Z-bands.