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. 2015 Oct 8;10(10):e0140292. doi: 10.1371/journal.pone.0140292

Fig 1. Phenotypic traits of Wrn Δhel/Δhel and Wrn -/- mice.

Fig 1

(A) Percentage of disease-free animals with age. The number of animals in each group is indicated (50% males + 50% females). (Log rank tests: WT vs. Wrn Δhel/Δhel mice, P = 6.8x10-5; WT vs. Wrn -/- mice, P = 0.001; Wrn Δhel/Δhel vs. Wrn -/- mice, P = 0.955). (B) Measures of males total body weight from the age of 4 to 52 weeks (n = 6–19 males). (C) Total body weight at four months of age (n = 6–10 males). (D) Ratio of spleen wet weight over total body weight at four months of age (n = 6 males). (E) Lymphocyte blood count at four months of age (n = 5 males). (F) Platelet blood count at four months of age (n = 5 males). (G) Red blood cell count at four months of age (n = 5 males). (H) % hematocrit at four months of age (n = 5 males). Bars in all the graphs represent SEM.