Table 3. Pearson's correlation coefficients between the tagged Wrn proteins and the indicated organelle markers a .
GFP-Wrn | GFP-WrnΔhel | DDK-Wrn | DDK-WrnΔhel | |
---|---|---|---|---|
ER (PDI) | 0.046 ± 0.065 | 0.741 ± 0.031 b | 0.097 ± 0.058 | 0.814 ± 0.017 b |
Peroxisome (Catalase) | 0.473 ± 0.043 | 0.644 ± 0.037 c | 0.242 ± 0.054 | 0.675 ± 0.029 c |
Lysosome (Lamp-1) | 0.237 ± 0.089 | 0.562 ± 0.037 | 0.242 ± 0.054 | 0.564 ± 0.055 |
Mitochondria (AIF) | 0.046 ± 0.037 | 0.416 ± 0.036 | -0.030 ± 0.042 | 0.612 ± 0.024 |
a Means of the calculated Pearson’s are indicated with the SEM. N = 3–5 cells for the GFP-Wrn and the DDK-Wrn constructs. N = 5–7 cells for the GFP-WrnΔhel and the DDK-WrnΔhel constructs.
b P < 0.05.
c P < 0.1.