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. 2015 Oct 8;10(10):e0139350. doi: 10.1371/journal.pone.0139350

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© 2015 Trentin-Sonoda et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — Data are mean ± SD; number of animals within the bars. (A and B) Serum urea and creatinine levels in TLR2^-/- and TLR4^-/- from I/R mice measured using the Analisa kit, and compared to those from the corresponding Sham (15 days after intervention), as indicated on the abscissae. * P <0.05 with respect to the Sham group (one-way ANOVA followed by Bonferroni post-test for selected pairs). (C and D) Kidney weight/body weight ratio (KW/BW) in TLR2^-/- and TLR4^-/- (Sham and I/R mice 15 days after intervention). Gray bars: left kidney; black bars: right kidney. (E and F) Renal vimentin mRNA levels in TLR2^-/- and TLR4^-/- (Sham and I/R mice 15 days after chirurgical intervention). Gray bars: left kidney; black bars: right kidney. In C to F: * P < 0.05 with respect to the corresponding Sham kidney (one way ANOVA followed by Bonferroni post-test for selected pairs). (G to I) TNF-α, IFN-γ and IL-1β serum levels from TLR2^-/- and TLR4^-/- mice (Sham and I/R, as shown on the abscissae, 15 days after intervention). *P < 0.05 when the I/R group was compared with the corresponding Sham (one-way ANOVA followed by Bonferroni post-test for selected pairs).