Table 2. Clinical characteristics, serum LIGHT levels, and Th1/Th2/Th17 cytokine levels in DM-IP patients.
| No | Sex | Age years | Disease type | IP progression | anti-MDA5ab | anti-ARSab | LIGHT pg/ml | INF-γ pg/ml | IL–2 pg/ml | TNF pg/ml | IL–10 pg/ml | IL–4 pg/ml | IL–6 pg/ml | IL–17 pg/ml | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 64 | CADM | RPIP | Pos | Neg | 150.1 | 28.7 | ND | ND | 5.3 | ND | 154.5 | 37.9 | Dead |
| 2 | F | 68 | CADM | CIP | Neg | Pos | 47.9 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 3 | M | 52 | CADM | RPIP | Pos | Neg | 335.4 | ND | ND | ND | ND | ND | 22.7 | ND | Dead |
| 4 | F | 50 | CADM | RPIP | Pos | Neg | 159.3 | ND | ND | ND | ND | ND | 20.4 | ND | Dead |
| 5 | M | 77 | DM | RPIP | Neg | Pos | 218.7 | ND | ND | ND | 12.2 | ND | 74.5 | ND | Dead* |
| 6 | M | 57 | CADM | RPIP | Neg | Pos | 261.3 | 17.5 | ND | ND | ND | ND | 14.8 | ND | Alive |
| 7 | F | 73 | DM | CIP | Neg | Neg | 102.3 | ND | ND | ND | ND | ND | 2.5 | ND | Alive |
| 8 | M | 78 | CADM | RPIP | Pos | Neg | 65.3 | ND | ND | ND | ND | ND | ND | ND | Dead |
| 9 | F | 49 | CADM | RPIP | Pos | Neg | 152.6 | ND | ND | ND | ND | ND | 16.6 | ND | Alive |
| 10 | F | 68 | DM | RPIP | Neg | Pos | 119 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 11 | F | 46 | CADM | RPIP | Neg | Neg | 116.7 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 12 | M | 67 | CADM | CIP | Neg | Neg | 56.8 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 13 | F | 61 | CADM | CIP | Neg | Pos | 94.3 | ND | ND | ND | ND | ND | 2.4 | ND | Alive |
| 14 | M | 67 | DM | RPIP | Neg | Pos | 258.3 | ND | ND | ND | ND | ND | 86.6 | ND | Alive |
| 15 | F | 77 | DM | CIP | Neg | Neg | 115.1 | 3.05 | ND | ND | ND | ND | ND | ND | Alive |
| 16 | F | 39 | DM | RPIP | Neg | Pos | 218 | ND | ND | ND | ND | ND | 12 | ND | Alive |
| 17 | F | 70 | CADM | RPIP | Pos | Neg | 96 | ND | ND | ND | ND | ND | 9.8 | ND | Alive |
| 18 | F | 51 | DM | RPIP | Pos | Neg | 49.6 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 19 | F | 43 | CADM | CIP | Pos | Pos | 164.2 | ND | ND | ND | ND | ND | 7.9 | ND | Alive |
| 20 | F | 53 | CADM | CIP | Neg | Neg | 16 | ND | ND | ND | ND | ND | ND | ND | Alive |
| 21 | F | 36 | CADM | RPIP | Neg | Pos | 236 | ND | ND | ND | ND | ND | 4.5 | ND | Alive |
DM: dermatomyositis; IP: interstitial pneumonia; F: female; M: male; CADM: clinically amyopathic DM; RPIP: rapidly progressive IP; CIP: chronic IP; ND: not detected; Pos: positive; Neg: negative; Dead: dead due to IP.
*Dead due to septic shock.