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. 2015 Oct 8;10(10):e0138598. doi: 10.1371/journal.pone.0138598

Fig 3. Cluster analysis of functional descriptors.

Fig 3

(A) Un-rooted tree based on all experimentally determined parameters (main dataset: k cat, K M, V max, k i and IC 50–values). (B) Un-rooted tree based on parameters related to basal enzymatic function and variables dependent on both affinity and reaction rate (sub-set A: k cat, K M, V max, k i-values). (C) Un-rooted tree based on parameters related to affinity (sub-set B: IC 50–values).