Table 4. Data quality control of 838 articles published in 1990, 2000, and 2010.
| Total | Article Year 1990(n = 223) | Article Year 2000(n = 314) | Article Year 2010(n = 301) | χ 2 | P * | |
|---|---|---|---|---|---|---|
| Trial registration | ||||||
| 175(20.9%) | 0(0.0%) | 0(0.0%) | 175(58.1%) | — | — | |
| Blindness | ||||||
| Open | 78(9.3%) | 22(9.9%) | 22(7.0%) | 34(11.3%) | 3.461 | 0.177 |
| Single-blind | 325(38.8%) | 75(33.6%) | 130(41.4%) | 120(39.9%) | 3.548 | 0.170 |
| Double-blind | 429(51.9%) | 126(56.5%) | 162(51.6%) | 147(48.8%) | 3.035 | 0.219 |
| Data entry | ||||||
| Single entry | 538(64.2%) | 185(83.0%) | 161(51.3%) | 192(63.8%) | 56.995 | <0.001 |
| Double entry | 106(12.6%) | 5(2.2%) | 11(3.5%) | 90(29.9%) | 126.703 | <0.001 |
| No mention | 194(23.2%) | 33(14.8%) | 142(45.2%) | 19(6.3%) | 142.699 | <0.001 |
| FAS-PPS-SS # | ||||||
| 476(56.8%) | 31(13.9%) | 215(68.5%) | 230(76.4%) | 231.864 | <0.001 |
*Chi-square test for differences by years.
#FAS- full analysis set, PPS -per-protocol set, SS-safety analysis set.