Figure 5.

Association between amyloid fibril deposits and macrophage recruitment.

Notes: ThT and anti-CD68 antibody staining revealed co-localization between macrophages and amyloid fibril deposition. In the lung (A), brain (B), and the liver (C) from MWCNT-exposed mice, with respect to the controls (a–c), increased numbers of macrophages are evident in exposed animals (d–f), which are associated with areas of amyloid deposition. The scale bar for all photographs =100 µm.

Abbreviations: ThT, Thioflavin T; MWCNT, multi-wall carbon nanotube.