Table 3.
Calculated daily dose of isoniazid in relative to NAT2 genotype and body weight using the developed model
| NAT2 status | Body weight, kg
|
||||
|---|---|---|---|---|---|
| 40 | 50 | 60 | 70 | 80 | |
| Slow-acetylators | 100 mg | 200 mg | 200 mg | 200 mg | 300 mg |
| Intermediate-acetylators | 200 mg | 200 mg | 300 mg | 300 mg | 300 mg |
| Rapid-acetylators | 300 mg | 300 mg | 300 mg | 400 mg | 400 mg |
Abbreviation: NAT2, N-acetyltransferase 2.