FIGURE 4. An inactive conformation of the WF finger.
(A) Upper panel: left to right: Cartoon model of the WF fingers from Atg101-Atg13 (closed conformation), Atg101 alone (Michel and Weiergraeber, unpublished RCSB entry 4WZG; unpublished RCSB entry)(open), and SpAtg101-Atg13 (4YK8)(open). Lower panel: left, comparison of the WF finger of Atg101-Atg13 and SpAtg101-Atg13; right, Atg101-Atg13 and Atg101 alone. The WF finger from human Atg101 is colored purple while that of fission yeast colored red. (B) The WF finger is partially buried by the residues around it. Cartoon (left) and surface representations (right) are shown here. Key residues are shown in a stick model.
