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. Author manuscript; available in PMC: 2016 Oct 6.
Published in final edited form as: Cell Metab. 2015 Aug 27;22(4):633–645. doi: 10.1016/j.cmet.2015.07.013

Figure 3. Restoration of PC synthesis through dietary choline rescues innate immune phenotypes in sams-1(RNAi) animals.

Figure 3

A. Heat map of genome wide expression changes in sams-1(RNAi), sams-1(RNAi) rescued by choline, or vector-only control (Vec) animals supplemented with choline. Heat map showing changes in expression level and choline rescue of lipogenic (B) and immune function (C) genes. Color values are shown in D. E. Control (Vec) or sams-1(RNAi) animals which were grown on normal media or media supplemented with dietary choline (CH) were immunoblotted with antibodies recognizing phospho-PMK-1, SAMS-1 or Histone 3.