FIG 6.
Enhanced survival of P. yoelii parasites within TfrcMRI24910/+ erythrocytes. Analysis was performed on labeled cells transfused into wild-type (A) or mutant (B) host animals infected with P. yoelii. Five wild-type and seven mutant host animals each received donor erythrocyte mixtures, labeled as follows: wild type-Atto 488/mutant-Atto 633 or wild type-Atto 633/mutant-Atto 488. Mutant and wild-type donor erythrocytes were obtained from three mice each and pooled before labeling. Analysis was conducted at the three time points indicated, and data in panels i to iv are presented as described in the legend to Fig. 5. Error bars indicate SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (as determined using the one-sample t test, with a ratio of 1 as the hypothetical mean for each time point).