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. 2015 Oct 8;83(11):4204–4216. doi: 10.1128/IAI.00643-15

TABLE 3.

Biophysical properties of treponemal Tp0751 orthologs

Tp0751 treponemal orthologa No. of amino acids (full length/signal sequence truncated) Molecular size (kDa) (full length/signal sequence truncated) pI (full length/signal sequence truncated) % Identity (L126-Y224/M1-P237)b Signal sequence prediction (SpI or SpII)c
T. paraluiscuniculi (p) 237/214 25.8/23.3 7.3/7.0 100/99 SpII (S23-C24)
T. phagedenis (strain 4A) (p) 497 56.3 5.5 47/13 NS
T. phagedenis (strain F0421) (p) 497 56.3 5.5 47/13 NS
T. vincentii (p) 477 54.5 5.0 40/12 NS
T. medium (p) 477 54.4 5.3 41/13 NS
T. pedis (p) 493 56.3 6.1 32/11 NS
T. denticola (p) 491 56.8 5.3 34/11 NS
T. lecithinolyticum (p) 508/494 57.0/55.5 5.5/5.3 30/11 SpII (A14-C15)
T. socranskii (p) 528 59.6 5.3 26/9 NS
T. saccharophilum (np) 792 89.0 4.9 26/8 NS
T. succinifaciens (np) 495 55.6 5.4 30/14 NS
T. primitia (np) 501 56.5 5.0 33/12 NS
T. paraluiscuniculi (p) 237/214 25.8/23.3 7.3/7.0 100/99 SpII (S23-C24)
a

p, pathogen; np, nonpathogen.

b

L126-Y224, conserved region of Tp0751; M1-P237, full-length Tp0751.

c

Cleavage sites are indicated in parentheses. NS, not secreted.