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Kaplan-Meier plot showing time to all-cause mortality according to the severity of functional mitral regurgitation (FMR) in 424 un-operated patients with non-ischemic FMR. Severe FMR defined as effective orifice area >0.2 cm2 or regurgitation volume >30 mL or vena contracta diameter >0.4 cm. Figure adapted from Rossi et al. (28).
