Table 5.
Overview of the patients’ functional recovery (post-test) in both domains, lesion volume, and percentage of damaged tissue in defined cortical and subcortical brain areas.
Pat. (base) |
Lesion volume to specific areas |
||||||||||
Outcome after 7-week therapy phase |
Total lesion volume |
Cortical (Lobar) |
Subcortical |
||||||||
Motor recovery | Language recovery | Fro | Par | Tem | Occ | Ins | Put | Tha | Cau | ||
1 (M+/L+) | Non-responder WMFT (o), DGI (o) |
Non-responder AAT (o), LEMO− |
10,325 | 2,403 | 6,368 | 2,409 | 335 | 1,903 | 437 | – | – |
2 (M−/L+) | Strong responder WMFT+, DGI+ |
Non-responder AAT (o), LEMO (o) |
6,852 | 5,815 | 3,193 | – | – | – | – | – | – |
3 (M+/L−) | Partial responder WMFT+, DGI (o) |
Strong Responder AAT+, LEMO+ |
14,406 | 8,422 | 4,171 | 1,255 | – | 2,764 | 732 | 23 | 25 |
4 (M−/L−) | Non-responder WMFT (o), DGI (o) |
Non-responder AAT (o), LEMO (o) |
50,472 | 18,747 | 16,884 | 9,692 | 7,556 | 3,340 | 1,237 | 87 | 12 |
+, Significant improvement; (o), no change; −, significant deterioration. Non-responder, patient showed no positive response to motor or language therapy; partial responder, partial positive response, i.e., significant improvement in one of the applied tests; strong responder, strong positive response, i.e., significant improvement in both applied tests; –, no lesion measured; Fro, frontal lobe; Par, parietal lobe; Tem, temporal lobe; Occ, occipital lobe; Ins, insula; Put, putamen; Tha, thalamus; Cau, nucleus caudate.
Lesion volume was calculated within the FLAIR data (voxels).