Table 5.
A list of some commercial non-setting CaPO4-based injectable bone substitutes (IBS) and pastes with indication of producer, product name, composition (when available) and form [848].
| Producer | Product name | Composition | Form |
|---|---|---|---|
| ApaTech (UK) | Actifuse™ | HA, polymer and aqueous solution | pre-mixed |
| Actifuse™ Shape; Actifuse™ ABX | Si-substituted CaPO4 and a polymer | pre-mixed | |
| Baxter (US) | TricOs Τ; TricOs | BCP (60% HA, 40% β-TCP) granules and Tissucol (fibrin glue) | to be mixed |
| Berkeley Advanced Biomaterials | Bi-Ostetic Putty | not disclosed | not disclosed |
| BioForm (US) | Calcium hydroxylapatite implant | HA powder embedded in a mixture of glycerine, water and CMC | pre-mixed |
| Biomatlante (FR) | In’Oss™ | BCP granules (60% HA, 40% β-TCP; 0.08–0.2 mm) and 2% HPMC | pre-mixed |
| MBCP Gel® | BCP granules (60% HA, 40% β-TCP; 0.08–0.2 mm) and 2% HPMC | pre-mixed | |
| Hydr’Os | BCP granules (60% HA, 40% β-TCP; micro- and nano-sized particles) and saline solution | pre-mixed | |
| Degradable solutions (CH) | Easy graft™ | β-TCP or BCP granules (0.45–l.0 mm) coated with 10 μm PLGA, N-methyl-2-pyrrolydone | to be mixed |
| Dentsply (US) | Pepgen P-15® flow | HA (0.25–0.42 mm), P-15 peptide and aqueous Na hyaluronate solution | to be mixed |
| DePuy Spine (US) | Healos® Fx | HA (20%–30%) and collagen | to be mixed |
| Fluidinova (P) | nanoXIM TCP | β-TCP (5% or 15%) and water | pre-mixed |
| nanoXIM HA | HA (5%, 15%, 30% or 40%) and water | pre-mixed | |
| Integra LifeSciences (US) | Mozaik Osteoconductive Scaffold | β-TCP (80%) and type 1 collagen (20%) | to be mixed |
| Mathys Ltd (CH) | Ceros® Putty/cyclOS® Putty | β-TCP granules (0.125–0.71 mm; 94%) and recombinant Na hyaluronate powder (6%) | to be mixed |
| Medtronic (US) | Mastergraft® | BCP (85% HA, 15% β-TCP) and bovine collagen | to be mixed |
| Merz Aesthetics (GER) | RADIESSE® | HA particles suspended in a gel | pre-mixed |
| Osartis / ΑΑΡ (GER) | Ostim® | Nanocrystalline HA (35%) and water (65%) | pre-mixed |
| Smith & Nephew (US) | JAXTCP | β-TCP granules and an aqueous solution of 1.75% CMC and 10% glycerol | to be mixed |
| Stryker (US) | Calstrux™ | β-TCP granules and CMC | to be mixed |
| Teknimed (FR) | Nanogel | HA (100 – 200 nm) (30%) and water (70%) | pre-mixed |
| Therics (US) | Therigraft™ Putty | β-TCP granules and polymer | pre-mixed |
| Zimmer (US) | Collagraft | BCP granules (65% HA, 35% β-TCP; 0.5–1.0 mm), bovine collagen and bone marrow aspirate | to be mixed |