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. 2015 Oct 9;5:14809. doi: 10.1038/srep14809

Figure 1. PICUP and SDS-PAGE analysis apparently indicate that Aβ40 and Aβ42 oligomerize through distinct pathways.

Figure 1

(a) LMW Aβ samples contain monomers in equilibrium with low order Aβ oligomers (left). Synthetic LMW_CL Aβ samples are obtained by subjecting their LMW counterparts to PICUP (right). (b) Characterization of LMW and LMW_CL Aβ40 and Aβ42 oligomer distribution by SDS-PAGE analysis. LMW_CL Aβ40 and Aβ42 samples were prepared using two different Aβ/Ru(bpy)32+/APS ratios, namely 1:2:5 and 1:2:40.