Figure 1.

Clustered saccharide patches exist at spatial scales spanning several orders of magnitude. Clustered saccharide patches may form on (A) heavily glycosylated proteins; (B) on cell membranes due to interactions between two or more glycosphingolipids; (C) or glycoproteins; (D) Clustered saccharide patches can also form on pathogen polysaccharides; (E) Glycosynapses are clustered glycan microdomains, which mediate cell-cell and cell-extracellular matrix adhesion and signaling. Arrows indicate likely clustered saccharide patches. Figure reproduced with permission [6].