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Metabolic network dysregulation associated with NAFLD. Major pathways contributing to NAFLD include dysregulations in fatty acid biosynthesis/oxidation, apoptosis, inflammation, ER stress, and mitochondria oxidative phosphorylation. Low-dose Cd-altered genes and metabolites were added to the KEGG metabolic pathways associated with NAFLD (http://www.genome.jp/kegg-bin/show_pathway?hsa04932+3643) and highlighted by green color.
